The BFCA Health Committee is
concerned that diabetes may be on the rise in Bichons, due to the
gradual increase in reports in the last few years. Diabetes may be
inherited but may also be an acquired or autoimmune disease. We are
searching for a canine diabetes research project that may help
answer this question. In the interim, at least we can inform you
about the disease.
Diabetes involves a deficiency in
insulin that is produced in the pancreas, which impairs the ability
of the tissues to use glucose, fats, and proteins. The prevalence
in dogs is 1/400-500 and Bichons are currently not included in the
breeds predisposed to this disease. The causes include genetic
susceptibility, pancreatitis, immune-mediated destruction of the
pancreas (due to the use of preventive medications for fleas and
ticks and excessive vaccinations), Cushing’s disease, viral
diseases, obesity, and some drugs can damage the pancreas such as
Steroids. The most common clinical signs are increased water intake
and accidents in the house due to excess urine volume. The
disease seems to be more severe if it occurs at a younger age.
Diabetes can be diagnosed by
testing the blood glucose level, which will be high due to the lack
of Insulin. Excess glucose will spill into the urine from the
kidneys, which can also be tested via a urine sample. Diagnosis
also involves ruling out another disease that presents with similar
clinical signs, Fanconi Syndrome. The kidneys, due to a
malfunction, spill glucose into the urine, but the blood glucose is
not elevated. The BFCA health committee has received only one
report of this syndrome, but be advised to ask your veterinarian
about this disease if symptoms persist despite Insulin therapy. At
this time researchers are not sure if the disease is inherited or
acquired. For more information on Fanconi Syndrome, and how to help
with research, see this web site:
http://www.caninegeneticdiseases.net/Fanconi/basicFAN.htm
The prognosis for diabetes with
proper treatment is good, with most dogs having a normal life span
as long as the glucose levels are managed properly. Treatment
involves giving Insulin injections daily, monitoring blood glucose
levels with your veterinarian, a diet with high fiber and low fat
(raw diet or dry kibble without grains), and weight loss if obese.
The optimal management is via a canine internist at a university
veterinary clinic. Complications include seizures or coma due to
alterations in blood glucose levels, and cataracts due to chronic
high glucose levels. Regular visits with a canine ophthalmologist
is absolutely necessary since poorly managed glucose levels can
cause cataracts that progress very quickly and may require surgery
to save the eyesight.
Until we know more about the
causes of diabetes, breeding advice is guarded. If you see a trend
toward diabetes in a family of Bichons, consider breeding away from
that line. Obtain either a blood glucose level or a urine test for
glucose before breeding. The fertility of dogs can be impacted by
diabetes, plus a diabetic bitch has a higher chance of problems with
pregnancy, whelping, and nursing.