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There is no doubt that allergy is the number
one health problem in Bichons. Ask anyone who has one and you will hear
about some form of allergy, even if it is only a mild seasonal itch.
Probably about half the Bichons out there have only a minor problem and
their owners don’t consider them to be “allergic” if the condition is not
year round or chronic. Yet most do have the urge to scratch or to bite at
themselves from time to time. This is a white breed and, like blondes in
the human world, they have more sensitive skin. Strong pigmentation may
offset that tendency so treasure those dogs with dark splotches on their
skin!
Then there are the dogs that have such severe problems that they self
mutilate with their constant scratching and chewing of themselves. While
these are in the minority, there are thousands of Bichons that show some
or all the assorted symptoms of allergy. Allergies can be food related but
most in the breed are probably atopy, a skin condition related to
inhalants. To further complicate matters for the dogs, the treatment of
allergy may be almost as bad as the disease. Overuse of corticosteroids to
control the itch sets the dogs up for a later occurrence of Cushing’s
syndrome, which can shorten life considerably.
Allergy itself is an autoimmune disease wherein the body attacks itself.
But this is only one of a number of related diseases that affect canines.
Found on a list of autoimmune conditions are those that may affect blood,
blood vessels, endocrine glands, eyes, gastrointestinal tract, kidneys,
musculoskeletal system, or nervous system. Virtually any part of the body
may have screwed up immunity that causes autoimmune response. To further
confuse the issue, veterinarians have, in the past, looked at these
diseases as separate from each other, not fully understanding the
relationship of one to the other.
With recent improvement in the understanding of autoimmunity, there is an
increase of research into this complex issue. BFCA has helped to fund
studies on allergy, as might be expected with this as our number one
health issue. It will take patience and a lot of money to dig into the
topic deeply enough to resolve the complicated and confusing processes
that create autoimmune response. In fact, the more we know, the more we
will realize what we do NOT know!
Immunity is nature’s very capable method whereby the body sends out
certain hormones to “defeat” or inhibit substances that are attacking the
body. A normal response goes after germs and controls the attacker before
the body, whether canine or human, becomes “sick” enough to cause concern.
In humans, we find we can “treat” a cold and it goes away in seven days.
Or we can let it run its course and we “get well” in a week. When the body
does not “cure” itself, we may have bronchitis or pneumonia as a secondary
infection and become really quite ill. This is a simplistic version of how
the body reacts normally.
When an abnormal response occurs, a different kind of result follows. The
dog that would scratch at a flea begins to attack his own body as the
inflammation becomes intolerable to him. What might have been, in a normal
dog, a quick bout of soft stools may become chronic gastritis or
inflammatory bowel disease. In the dog with a compromised immune system,
the pancreas may trigger a diabetic condition or adrenal glands may change
previously healthy adrenal glands to develop either Cushing’s or Addison’s
disease. Such is the nature of autoimmune response. Immune mediated
disease is a case of genes gone haywire and the resulting effect is
complex, probably because of several genetic risk factors that combine
during the same period of time and also affected by outside phenomena.
What outside conditions may start this generalized response? The immune
system may be affected by such additional risk factors as environmental
conditions, possibly chemical or physical changes, or stress. One stress
factor that is being investigated is the effect on the total body at the
time of vaccination, including boosters. Chemicals used for cleaning and
in pest control are part of environmental changes. This is especially
important in animals receiving preventive chemicals to control fleas,
ticks and parasites. Therefore in judging your dog’s environment, you
should certainly be aware of cleaning products, sprays and fertilizers or
other products containing dangerous chemicals and poisons. Be cautious in
using any of these substances. The dog that is being treated topically or
internally with preventive medications may be getting a double or triple
attack on his body!
Any discussion of treating immune mediated disease must include the use of
steroids to treat these diseases. Corticosteroids are hormones that are
both anti-inflammatory and immunosuppressive in their action. As
previously stated, as anti-inflammatory drugs, they calm down the
inflammation that causes the itch in allergy. At the same time, the drugs
suppress the immune response that protects the body from invasive disease
elements. It is also important to remember that there is no way to
separate these actions. It is constantly a challenge to balance the two
actions, one against the other, also necessitating a gradual decrease in
the drug when the dog is taken off the medication.
One other important issue is the effect upon several organs of the body,
regardless of which organ or system is targeted for treatment. In other
words, whether it is a skin problem or a blood disorder, there will at the
same time be some residual effect on the metabolic system, the heart,
liver, kidneys and endocrine systems. These drugs alter appetite, cause
behavioral changes, and may affect bone growth. Prednisone is one drug
specifically mentioned to avoid when treating dogs with calcium oxalate
bladder stones, the most common form of stone formation in Bichons.
Safer alternatives to treat allergy should be used for milder attacks.
Antihistamines are a type of drug that counter formation of histamine in
the body. Histamine occurs in response to allergens. It has been
determined that fatty acids omega 6 and omega 3 also are beneficial to
boost immune response. Any boost to the immune system has a positive
effect overall so this is one supplement that would be useful for all
Bichons. Vitamins are not as useful and in a breed that is susceptible to
calcium stone formation, extra vitamin C could have an adverse effect.
The breeder with dogs known to suffer allergy should be extremely careful
in using those dogs in his/her breeding program. Since autoimmunity is an
ongoing issue in Bichons, given their tendency to show signs of allergies,
it has to be assumed that any Bichon may carry the genetic components that
will allow that dog and its offspring to be at risk for other immunity
problems. There is definitely an increase in all breeds to develop immune
mediated diseases and we do get many reports of Bichons with thyroid
problems, diabetes and Cushings, for instance. Immune mediated blood
disorders are on the increase. Therefore it pays the breeder to remove
from his/her breeding program any Bichon that has developed serious
allergy or has produced offspring with severe allergies. At the very
least, do NOT repeat that particular breeding which has shown evidence of
a compromised immune system.
Several recent articles have addressed various factors that affect immune
response. They will be listed below. Note that several address a holistic
approach to treatment. It behooves each of us to go back to any of the
articles or seminars by W. Jean Dodds DVM because her concerns are now
being proven to be on the mark, including her theories of predisposition
in certain breeds, including the Bichon Frise, to suffer genetic immune
mediated disease. In BFCA health data for the past 10 years, we have
documented numerous Bichons with autoimmune problems. Based on those
figures, we know that allergy is the primary problem but one has to
consider any dog with allergy to be immune compromised and therefore
susceptible to any of the other immune mediated diseases!
Articles of interest are:
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Any article by W. Jean Dodds DVM addressing the topic of immunity;
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”Their Own Worst Enemy”, AKC GAZETTE, August 2004, page 4;
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“Walking the Allergy Maze”, THE WHOLE DOG JOURNAL”, August 2004, page 3;
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“Use Corticosteroids with Caution”, THE WHOLE DOG JOURNAL, July 2004, page 8
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